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Multiple Testing Procedures with Applications to Genomics (Springer Series in Statistics) Book
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.Read More
from£87.32 | RRP: * Excludes Voucher Code Discount Also available Used from £8.68
- 3897496887
- 9783897496880
- Sandrine Dudoit, Mark J. van der Laan
- 25 January 2008
- Springer
- Hardcover (Book)
- 590
- 1
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